🛡️ Immune SupportPreclinical

LL-37

Cathelicidin · CAMP Peptide · hCAP18

A natural antimicrobial peptide with broad-spectrum immune defense

Typical Dose

1–5 mg per day

Route

Subcutaneous

Frequency

Once daily

Cycle

4–8 weeks

Overview

LL-37 is your body's own natural antibiotic. It is the only cathelicidin peptide that humans produce, and it is part of your innate immune system — the first line of defense that kicks in before your body has time to build a specific immune response. It kills bacteria, viruses, and fungi by punching holes in their cell membranes. It is found in your skin, lungs, and gut, and it also plays a role in wound healing. Researchers are interested in it as a potential alternative to conventional antibiotics, especially for drug-resistant infections.

Key Benefits

Broad-spectrum antimicrobial activity

Antiviral properties

Promotes wound healing

Modulates inflammatory response

Protects against bacterial biofilms

Supports skin barrier function

Mechanism of Action

LL-37 works like a molecular weapon against pathogens. Bacteria have a negative charge on their outer membrane, and LL-37 has a positive charge — so it is attracted to bacteria and sticks to them. Once attached, it punches holes in the bacterial membrane, causing the cell to fall apart. It also acts as an alarm signal to the rest of the immune system, recruiting more immune cells to the area. In wound healing, it promotes new blood vessel growth and helps cells migrate to close the wound.

Dosing Protocol

Typical Dose

1–5 mg per day

Dose Range

Variable

Frequency

Once daily

Route

Subcutaneous injection or topical

Cycle Length

4–8 weeks

CLINICAL NOTES

Topical application is effective for skin infections and wound healing. Systemic use is less common and dosing is still being established.

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Reconstitution calculator and cycle planner pre-filled with LL-37 defaults

Side Effects & Safety

Local irritation with topical use

Injection site reactions

Limited systemic data available

IMPORTANT DISCLAIMER

This information is for educational purposes only. Always consult a qualified healthcare provider before starting any peptide protocol. Individual responses vary and medical supervision is recommended.